Discovery of an Angiotensin II Binding Inhibitor from a Cytospora sp. Using Semi-automated Screening Procedures.
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چکیده
منابع مشابه
Discovery of an angiotensin II binding inhibitor from a Cytospora sp. using semi-automated screening procedures.
Cytosporin A, B and C, three antagonists of [125I]-angiotensin II binding to rat adrenal glands were discovered in fermentations of an endophytic Cytospora sp. during routine screening using semi-automated procedures. The most potent of these displayed an IC50 of 1.5-3 microM and was specific for angiotensin II AT2.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1996
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.49.119